Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGF2 | P09038 | 1/20 | 0.37 |
| ▸ | IDUA | P35475 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | M6PR | P20645 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.33 |
| ▸ | HPSE | Q9Y251 | 3/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13814803 | 1.00 | FGF2 (0.37) | FGF2IDUAAKT1SUCNR1M6PR | |
| SCHEMBL18372818 | 1.00 | FGF2 (0.37) | FGF2IDUAAKT1SUCNR1M6PR | |
| SCHEMBL13642457 | 0.89 | AKT1 (0.36) | FGF2IDUAAKT1SUCNR1M6PR | |
| SCHEMBL24694355 | 0.86 | FGF2 (0.43) | FGF2IDUAAKT1SUCNR1M6PR | |
| SCHEMBL6123480 | 0.85 | M6PR (0.36) | FGF2SUCNR1M6PRLGALS8 | |
| SCHEMBL12703785 | 0.85 | M6PR (0.36) | FGF2SUCNR1M6PRLGALS8 | |
| SCHEMBL21540433 | 0.85 | M6PR (0.41) | FGF2AKT1SUCNR1M6PRKDM4E | |
| SCHEMBL21065667 | 0.85 | M6PR (0.38) | FGF2IDUAAKT1SUCNR1M6PR | |
| SCHEMBL18412631 | 0.85 | M6PR (0.38) | FGF2IDUAAKT1SUCNR1M6PR | |
| SCHEMBL13901005 | 0.85 | M6PR (0.41) | FGF2AKT1SUCNR1M6PRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006052886-A1 | METABOLITES OF CERTAIN [1,4]DIAZEPINO[6,7,1-IJ]QUINOLINE DERIVATIVES AND METHODS OF PREPARATION AND USE THEREOF | WYETH (US) | 2006-05-18 | — | — | WO | disclosed |