Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | CTSS | P25774 | 3/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 7/20 | 0.44 |
| ▸ | IDE | P14735 | 2/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | PPM1D | O15297 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5506241 | 0.89 | CTSL (0.57) | KMT2AMEN1CTSLCTSSCTSB | |
| SCHEMBL8269807 | 0.85 | REN (0.47) | KMT2AMEN1CTSLCTSSCTSB | |
| SCHEMBL10069021 | 0.80 | REN (0.47) | CTSSRENCTSD | |
| SCHEMBL1863290 | 0.80 | REN (0.59) | REN | |
| SCHEMBL1863288 | 0.80 | REN (0.59) | REN | |
| SCHEMBL1863291 | 0.80 | REN (0.59) | REN | |
| SCHEMBL1868456 | 0.80 | REN (0.59) | REN | |
| SCHEMBL1863073 | 0.80 | REN (0.56) | REN | |
| SCHEMBL1857281 | 0.80 | REN (0.56) | REN | |
| SCHEMBL12669834 | 0.80 | REN (0.46) | CTSLCTSSREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006042150-A1 | DIAMINOALKANE ASPARTIC PROTEASE INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2006-04-20 | — | — | WO | disclosed |