Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 14/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | FAP | Q12884 | 3/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL497449 | 0.87 | DPP4 (0.50) | DPP4GAARAB9ALMNATSHR | |
| SCHEMBL638215 | 0.83 | DPP4 (0.55) | DPP4RAB9AFAPCHRM1SMN1; SMN2 | |
| SCHEMBL20041920 | 0.83 | DPP4 (0.66) | DPP4RAB9ADPP9LMNATSHR | |
| SCHEMBL8273204 | 0.83 | DPP4 (0.45) | DPP4DPP9FAPCHRM1 | |
| SCHEMBL8272012 | 0.81 | DPP4 (0.44) | DPP4DPP9FAPCHRM1 | |
| SCHEMBL8273201 | 0.81 | DPP4 (0.44) | DPP4DPP9FAPCHRM1 | |
| SCHEMBL20041950 | 0.81 | DPP4 (0.63) | DPP4GAARAB9ADPP9FAP | |
| SCHEMBL3917633 | 0.81 | DPP4 (0.54) | DPP4GAARAB9ADPP9FAP | |
| SCHEMBL3918551 | 0.78 | DPP4 (0.51) | DPP4RAB9ADPP9FAPCHRM1 | |
| SCHEMBL637987 | 0.78 | DPP4 (0.64) | DPP4RAB9ADPP9FAPCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006048427-A1 | METHOD FOR PRODUCING CHIRAL 8-(3-AMINO-PIPERIDIN-1-YL)-XANTHINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-05-11 | — | — | WO | disclosed |