SCHEMBL8268293 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	ALDH1A1	P00352	1/20	0.39

▸	LMNA	P02545	1/20	0.39

▸	TSHR	P16473	3/20	0.34

▸	BRD4	O60885	1/20	0.34

▸	GAA	P10253	2/20	0.32

▸	HSD17B10	Q99714	1/20	0.32

▸	MGAM	O43451	1/20	0.32

▸	SI	P14410	1/20	0.32

▸	MGAM2	Q2M2H8	1/20	0.32

▸	EGFR	P00533	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL10778868	0.80	ALDH1A1 (0.36)	ALDH1A1LMNATSHRBRD4GAA
SCHEMBL10727016	0.78	BRD4 (0.40)	ALDH1A1LMNABRD4GAAEGFR
SCHEMBL5638546	0.77	TSHR (0.46)	TSHRBRD4GAAHSD17B10MGAM
SCHEMBL5638542	0.77	TSHR (0.46)	TSHRBRD4GAAHSD17B10MGAM
SCHEMBL14499820	0.77	TSHR (0.46)	TSHRBRD4GAAHSD17B10MGAM
SCHEMBL8013795	0.75	—	—
SCHEMBL5765816	0.75	SLC6A1 (0.34)	ALDH1A1LMNA
SCHEMBL5765812	0.75	SLC6A1 (0.34)	ALDH1A1LMNA
SCHEMBL1863234	0.73	—	—
SCHEMBL18893361	0.71	ALDH1A1 (0.32)	ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2006043145-A1	INHIBITORS OF HEPATITIS C VIRUS PROTEASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME	PFIZER INC. (US)	2006-04-27	—	—	WO	disclosed