Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 15/20 | 0.65 |
| ▸ | PDE4B | Q07343 | 18/20 | 0.47 |
| ▸ | PDE4A | P27815 | 12/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 11/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8268467 | 0.93 | PDE4D (0.65) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL8267963 | 0.91 | PDE4D (0.67) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL4026556 | 0.80 | PDE4D (0.73) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| Oglemilast SCHEMBL4030005 | 0.80 | PDE4D (0.98) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| Oglemilast SCHEMBL4030019 | 0.80 | PDE4D (0.98) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL4026259 | 0.80 | PDE4D (0.73) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| Oglemilast SCHEMBL29413215 | 0.79 | PDE4D (1.00) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| Oglemilast SCHEMBL29369504 | 0.79 | PDE4D (1.00) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| Oglemilast SCHEMBL220245 | 0.79 | PDE4D (1.00) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL4755347 | 0.79 | PDE4D (0.69) | PDE4DPDE4BPDE4APDE4CABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006051390-A1 | HETEROCYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND METHODS OF PREPARING THEM | GLENMARK PHARMACEUTICALS S.A. (US) | 2006-05-18 | — | — | WO | disclosed |