Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 11/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6391427 | 0.71 | AVPR1A (0.43) | AVPR1ASIGMAR1 | |
| SCHEMBL5280469 | 0.69 | NPC1 (0.47) | AVPR1ASIGMAR1OXTR | |
| SCHEMBL19608944 | 0.67 | ALDH1A1 (0.58) | SIGMAR1 | |
| SCHEMBL5281210 | 0.66 | AVPR1A (0.46) | AVPR1A | |
| SCHEMBL5343964 | 0.65 | AVPR1A (0.47) | AVPR1ASIGMAR1 | |
| SCHEMBL15963361 | 0.64 | SIGMAR1 (0.59) | AVPR1ASIGMAR1 | |
| SCHEMBL15963350 | 0.64 | ALDH1A1 (0.54) | SIGMAR1 | |
| SCHEMBL6919513 | 0.63 | SIGMAR1 (0.57) | SIGMAR1 | |
| SCHEMBL13610481 | 0.62 | SIGMAR1 (0.53) | AVPR1ASIGMAR1 | |
| SCHEMBL9615977 | 0.62 | SIGMAR1 (0.54) | AVPR1ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006002284-A1 | UBIQUITIN LIGASE INHIBITORS | RIGEL PHARMACEUTICALS, INC. (US) | 2006-01-05 | — | — | WO | disclosed |