⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8268591 | 0.85 | — | — | |
| SCHEMBL8268592 | 0.83 | ALDH1A1 (0.48) | — | |
| SCHEMBL8268589 | 0.81 | ALDH1A1 (0.52) | — | |
| SCHEMBL56801 | 0.78 | — | — | |
| SCHEMBL13821706 | 0.77 | — | — | |
| SCHEMBL12835123 | 0.76 | — | — | |
| SCHEMBL17962968 | 0.74 | — | — | |
| SCHEMBL14239078 | 0.74 | — | — | |
| SCHEMBL8676336 | 0.72 | — | — | |
| SCHEMBL8268595 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080027127-A1 | Trans Pyrrolidinyl Derivates and Their Pharmaceutical Use | FAUST PHARMACEUTICALS (FR) | 2008-01-31 | — | — | US | disclosed |
| WO-2005118533-A1 | TRANS PYRROLIDINYL DERIVATIVES AND THEIR PHARMACEUTICAL USE | FAUST PHARMACEUTICALS (FR) | 2005-12-15 | — | — | WO | disclosed |