Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | DGKA | P23743 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8268589 | 0.98 | ALDH1A1 (0.52) | ALDH1A1TSHRTP53DGKA | |
| SCHEMBL8268591 | 0.93 | — | — | |
| SCHEMBL8268587 | 0.83 | — | — | |
| SCHEMBL6053378 | 0.81 | — | — | |
| SCHEMBL13186365 | 0.79 | ALDH1A1 (0.64) | ALDH1A1TSHR | |
| SCHEMBL27508617 | 0.79 | ALDH1A1 (0.64) | ALDH1A1TSHRTP53DGKARECQL | |
| SCHEMBL8465379 | 0.79 | ALDH1A1 (0.64) | ALDH1A1TSHRTP53DGKARECQL | |
| Methylene Chloride SCHEMBL1421250 | 0.77 | ALDH1A1 (0.56) | ALDH1A1TSHRTP53DGKARECQL | |
| SCHEMBL16349369 | 0.77 | PAOX (0.48) | ALDH1A1TSHRDGKA | |
| SCHEMBL12824091 | 0.77 | ALDH1A1 (0.68) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080027127-A1 | Trans Pyrrolidinyl Derivates and Their Pharmaceutical Use | FAUST PHARMACEUTICALS (FR) | 2008-01-31 | — | — | US | disclosed |
| WO-2005118533-A1 | TRANS PYRROLIDINYL DERIVATIVES AND THEIR PHARMACEUTICAL USE | FAUST PHARMACEUTICALS (FR) | 2005-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027127-A1 | Trans Pyrrolidinyl Derivates and Their Pharmaceutical Use | SUCNR1, GLRA1, CNR1 | ALDH1A1 1888/4885TSHR 62/4885TP53 2077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.