Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 16/20 | 0.76 |
| ▸ | PDE4B | Q07343 | 19/20 | 0.51 |
| ▸ | PDE4A | P27815 | 15/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 15/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13632173 | 0.88 | PDE4D (0.59) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL4029909 | 0.88 | PDE4D (0.81) | PDE4DPDE4BPDE4APDE4C | |
| Oglemilast SCHEMBL29369504 | 0.86 | PDE4D (1.00) | PDE4DPDE4BPDE4APDE4C | |
| Oglemilast SCHEMBL29413215 | 0.86 | PDE4D (1.00) | PDE4DPDE4BPDE4APDE4C | |
| Oglemilast SCHEMBL220245 | 0.86 | PDE4D (1.00) | PDE4DPDE4BPDE4APDE4C | |
| Oglemilast SCHEMBL4030005 | 0.86 | PDE4D (0.98) | PDE4DPDE4BPDE4APDE4C | |
| Oglemilast SCHEMBL4030019 | 0.86 | PDE4D (0.98) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL5022733 | 0.83 | PDE4B (0.52) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL13794644 | 0.83 | PDE4D (0.74) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL4029740 | 0.80 | PDE4D (0.69) | PDE4DPDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090281146-A1 | PROCESS FOR THE PREPARATION OF N-(3,5-DICHLOROPYRID-4-YL)-4-DIFLUOROMETHOXY-8-METHANESULFONAMIDO-DIBENZO[B,D]FURAN-1-CARBOXAMIDE | GLENMARK PHARMACEUTICALS, S.A. (CH) | 2009-11-12 | — | — | US | disclosed |
| US-7563900-B2 | Process for the preparation N-(3,5-dichloropyrid-4-yl)-4-difluoromethoxy-8-methane sulfonamido-dibenzo[b,d]furan-1-carboxamide | GLENMARK PHARMACEUTICALS S.A. (CH) | 2009-07-21 | — | — | US | disclosed |
| WO-2006040652-A2 | PROCESS FOR THE PREPARATION OF N-(3,5-DICHLOROPYRID-4-YL)-4DIFLUOROMETHOXY-8-METHANESULFONAMIDO-DIBENZO[B,D]FURAN-1-CARBOXAMIDE | GLENMARK PHARMACEUTICALS S.A. (US) | 2006-04-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281146-A1 | PROCESS FOR THE PREPARATION OF N-(3,5-DICHLOROPYRID-4-YL)-4-DIFLUOROMETHOXY-8-METHANESULFONAMIDO-DIBENZO[B,D]FURAN-1-CARBOXAMIDE | DHODH, QDPR, DPYD | PDE4D 278/4885PDE4B 587/4885PDE4A 1099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.