Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.32 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.32 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.32 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.32 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.32 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.32 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.32 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.32 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5044573 | 0.79 | GAA (0.60) | GAA | |
| SCHEMBL9214465 | 0.78 | GAA (0.55) | GAA | |
| SCHEMBL7951439 | 0.77 | GAA (0.48) | GAA | |
| SCHEMBL11038245 | 0.75 | GAA (0.53) | GAA | |
| SCHEMBL18403857 | 0.74 | GSK3A (0.43) | ADCY6ADCY3ADCY9ADCY5ADCY8 | |
| SCHEMBL9214873 | 0.74 | GAA (0.48) | GAA | |
| SCHEMBL21550076 | 0.73 | GAA (0.50) | GAA | |
| SCHEMBL28634068 | 0.70 | GAA (0.58) | GAA | |
| SCHEMBL11041593 | 0.70 | GAA (0.51) | GAA | |
| SCHEMBL3132084 | 0.69 | GAA (0.54) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005111026-A1 | NOVEL METHOD OF SYNTHESISING 1,3-DIHYDRO-2H-3-BENZAZEPIN-2-ONE DERIVATIVES AND USE THEREOF IN THE SYNTHESIS OF IVABRADINE AND THE SALTS THEREOF FOR ADDITION TO A PHARMACEUTICALLY ACCEPTABLE ACID | LES LABOIRATOIRES SERVIER (FR) | 2005-11-24 | — | — | WO | disclosed |