Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7951439 | 0.85 | GAA (0.48) | GAA | |
| SCHEMBL9214465 | 0.79 | GAA (0.55) | GAA | |
| SCHEMBL11041593 | 0.78 | GAA (0.51) | GAA | |
| SCHEMBL7951440 | 0.78 | GAA (0.44) | GAA | |
| SCHEMBL8268993 | 0.75 | GAA (0.51) | GAA | |
| SCHEMBL9214873 | 0.75 | GAA (0.48) | GAA | |
| SCHEMBL333847 | 0.75 | GAA (0.63) | GAAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL15906664 | 0.70 | GAA (0.57) | GAA | |
| SCHEMBL11038801 | 0.69 | — | — | |
| SCHEMBL5044573 | 0.69 | GAA (0.60) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116444-A2 | Improvements in or relating to benzazepine derivatives | ELI LILLY AND COMPANY (US) | 1984-08-22 | — | — | EP | disclosed |