Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 12/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.50 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1320535 | 0.84 | HDAC6 (0.64) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL1320536 | 0.84 | HDAC6 (0.64) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL12426309 | 0.78 | HSD11B1 (0.67) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL14244403 | 0.78 | HSD11B1 (0.67) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL14244352 | 0.71 | HDAC4 (0.67) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL12425750 | 0.71 | HDAC4 (0.67) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL3469142 | 0.71 | HDAC2 (0.64) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL362072 | 0.70 | ESR1 (0.61) | — | |
| SCHEMBL1319893 | 0.70 | SNCA (0.63) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL1319897 | 0.70 | SNCA (0.63) | HDAC1HDAC6HDAC3HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006037761-A1 | NEW HISTONE DEACETYLASES INHIBITORS | DAC S.R.L. (IT) | 2006-04-13 | — | — | WO | disclosed |