Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 9/20 | 0.67 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6337481 | 0.99 | MME (0.68) | MMECHRM5CHRM1MMP1CHRM4 | |
| SCHEMBL6339711 | 0.99 | MME (0.68) | MMECHRM5CHRM1MMP1CHRM4 | |
| SCHEMBL8270495 | 0.90 | MME (0.54) | MMECHRM5CHRM1MMP1CHRM4 | |
| SCHEMBL8271281 | 0.85 | MME (0.65) | MMEMMP1 | |
| SCHEMBL6349761 | 0.80 | MME (1.00) | MMEMMP1RAB9ANPC1 | |
| SCHEMBL489205 | 0.80 | MME (1.00) | MMEMMP1 | |
| SCHEMBL6340259 | 0.80 | MME (0.82) | MMEMMP1POLB | |
| SCHEMBL1620495 | 0.80 | MME (1.00) | MMEMMP1 | |
| SCHEMBL8268609 | 0.79 | RAB9A (0.45) | MMECHRM5CHRM1CHRM4CHRM3 | |
| SCHEMBL8269280 | 0.76 | MME (0.53) | MMEMMP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006027680-A1 | 3-(1-CARBAMOYLCYCLOHEXYL) PROPIONIC ACID DERIVATIVES AS INHIBITORS OF NEUTRAL ENDOPEPTIDASE ENZYME | PFIZER LIMITED (GB) | 2006-03-16 | — | — | WO | disclosed |