SCHEMBL827253

SCHEMBL827253

CC(Cl)N1CCCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14136210 1.00 FDPS (0.35)
Hydrochloric Acid SCHEMBL384684 0.97 SMN1; SMN2 (0.35)
SCHEMBL1339269 0.97
Bromide SCHEMBL2225990 0.94
Hydrochloric Acid SCHEMBL1897139 0.94
Formamide SCHEMBL11268980 0.85 LMNA (0.36)
SCHEMBL11570562 0.83
SCHEMBL8026943 0.75 SMN1; SMN2 (0.37)
SCHEMBL1741714 0.73
SCHEMBL11582857 0.73 FDPS (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190152891-A1 COMPLEX AND STRUCTURALLY DIVERSE COMPOUNDS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2019-05-23 US claimed
CN-103865022-B A kind of compound alkali ionic liquid preparing high flame retardant hard polyaminoester sheet material for catalysis SHANDONG PLANT PANEL CO., LTD. (CN) 2016-04-27 CN claimed
EP-2987533-A1 7-substituted piperazin-1-yl fluoroquinolone compounds, their use in the treatment of cancer, pharmaceutical compositions and a method for preparation King Saud University (SA) 2016-02-24 EP claimed
US-20150274638-A1 COMPLEX AND STRUCTURALLY DIVERSE COMPOUNDS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2015-10-01 US claimed
CN-103865022-A Compound alkaline ionic liquid for catalytically preparing high-flame retardant hard polyurethane plate SHANDONG PLANT PANEL CO LTD 2014-06-18 CN claimed
WO-2013142873-A2 COMPLEX AND STRUCTURALLY DIVERSE COMPOUNDS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2013-09-26 WO claimed
US-20050085555-A1 Composition, synthesis and therapeutic applications of polyamines MURPHY, MICHAEL A. 2005-04-21 US claimed
EP-0272226-B1 8-AZAXANTHINES ALKYLAMINOALKYL OR HETEROCYCLYLALKYL-SUBSTITUTED ON THE TRIAZOLE RING, THE SALTS THEREOF WHICH ARE PHYSIOLOGICALLY ACCEPTABLE, THEIR PHARMACEUTICAL COMPOSITIONS HAVING ANTIBRONCHOSPASTIC ACIVITY, AND THE PROCESS FOR PREPARING THE SAME MALESCI ISTITUTO FARMACOBIOLOGICO S.p.A. (IT) 1991-11-27 EP claimed
EP-0385491-A1 Optically active isomer of cloperastine possessing antitussive activity, a process for its preparation and pharmaceutical compositions which contain it MAGIS FARMACEUTICI S.p.A. (IT) 1990-09-05 EP claimed
EP-0341066-A2 Immunostimulating guanine derivatives, compositions and methods SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) 1989-11-08 EP claimed
WO-2023205475-A1 CTPS1 INHIBITORS AND USES THEREOF NIMBUS CLOTHO, INC. (US) 2023-10-26 WO disclosed
US-10800730-B2 Complex and structurally diverse compounds THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2020-10-13 US disclosed
US-20190152891-A1 COMPLEX AND STRUCTURALLY DIVERSE COMPOUNDS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2019-05-23 US disclosed
US-10081592-B2 Complex and structurally diverse compounds THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2018-09-25 US disclosed
CN-108558860-A A kind of new method of synthesis umeclidinium 成都伊诺达博医药科技有限公司 2018-09-21 CN disclosed
US-4010272-A ANTHELMINTICALLY ACTIVE BASICALLY SUBSTITUTED 2-CARBALKOXY-AMINO-BENZIMIDAZOLYL-5(6)-PHENYL ETHERS AND -KETONES HOECHST AKTIENGESELLSCHAFT (DT) 1977-03-01 US disclosed
US-4008223-A SPASMOLYTIC, ANTIPHLOGISTIC, TRANQUILIZER DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1977-02-15 US disclosed
US-4005095-A PERIPHERAL-CORONARY-CEREBRAL VASODILATORS, DECONGESTANTS, SPASMOLYTIC AND PAPAVERINE-LIKE ACTIVITY INNOTHERA (FR) 1977-01-25 US disclosed
US-4002633-A FOR TREATING CARDIOVASCULAR DISORDERS OMNIUM CHIMIQUE SOCIETE ANONYME (BE) 1977-01-11 US disclosed
US-3994890-A TRANQUILIZERS, ANTIDEPRESSANTS, ANTIINFLAMMATORY CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) 1976-11-30 US disclosed