Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 2/20 | 0.37 |
| ▸ | KRAS | P01116 | 2/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.36 |
| ▸ | NQO1 | P15559 | 1/20 | 0.36 |
| ▸ | EDNRB | P24530 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13012202 | 0.89 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1ALDH1A1MAPK1RAB9A | |
| SCHEMBL21494963 | 0.85 | ALDH1A1 (0.38) | SMN1; SMN2NPC1ALDH1A1MAPK1RAB9A | |
| SCHEMBL13267964 | 0.85 | NOS3 (0.38) | SMN1; SMN2NPC1ALDH1A1MAPK1RAB9A | |
| SCHEMBL10854375 | 0.83 | SMN1; SMN2 (0.38) | SMN1; SMN2NPC1ALDH1A1MAPK1RAB9A | |
| SCHEMBL22681208 | 0.82 | KRAS (0.36) | SMN1; SMN2NPC1ALDH1A1MAPK1RAB9A | |
| SCHEMBL13248471 | 0.82 | HMGCR (0.36) | SMN1; SMN2NPC1ALDH1A1MAPK1RAB9A | |
| SCHEMBL3825486 | 0.80 | MEN1 (0.42) | SMN1; SMN2NPC1ALDH1A1MAPK1RAB9A | |
| SCHEMBL4469982 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1ALDH1A1MAPK1RAB9A | |
| SCHEMBL6336311 | 0.78 | ALDH1A1 (0.41) | SMN1; SMN2NPC1ALDH1A1MAPK1RAB9A | |
| SCHEMBL9432444 | 0.78 | KDM4E (0.42) | SMN1; SMN2NPC1ALDH1A1MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2725022-B1 | New amides as pest control agents | BAYER CROPSCIENCE AG (DE) | 2017-03-29 | — | — | EP | claimed |
| EP-2297130-B1 | NEW HETEROAROMATIC AMIDES AND THIOAMIDES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AG (DE) | 2014-09-17 | — | — | EP | claimed |
| EP-3728223-B1 | CYCLOHEXYL ACID TRIAZOLE AZINES AS LPA ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2022-12-28 | — | — | EP | disclosed |
| US-20170165265-A1 | HEAT SHOCK PROTEIN BINDING COMPOUNDS, COMPOSITIONS, AND METHODS FOR MAKING AND USING SAME | MEMORIAL SLOAN-KETTERING CANCER CENTER | 2017-06-15 | — | — | US | disclosed |
| EP-2725022-B1 | New amides as pest control agents | BAYER CROPSCIENCE AG (DE) | 2017-03-29 | — | — | EP | disclosed |
| US-9567318-B2 | Substituted pyrimidine compounds and uses thereof | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2017-02-14 | — | — | US | disclosed |
| EP-2730569-B1 | New amides and thioamides as pest control agents | BAYER CROPSCIENCE AG (DE) | 2016-11-30 | — | — | EP | disclosed |
| US-20160316755-A1 | Novel Heteroaromatic Amides and Thioamides as Pesticides | BAYER CROPSCIENCE AG (DE) | 2016-11-03 | — | — | US | disclosed |
| US-9428487-B2 | Heteroaromatic amides and thioamides as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-08-30 | — | — | US | disclosed |
| EP-2297130-B1 | NEW HETEROAROMATIC AMIDES AND THIOAMIDES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AG (DE) | 2014-09-17 | — | — | EP | disclosed |
| EP-2730568-A1 | NEW HETEROAROMATIC AMIDES AND THIOAMIDES AS PEST CONTROL AGENTS | Bayer CropScience AG (DE) | 2014-05-14 | — | — | EP | disclosed |
| US-20110118290-A1 | Novel Amides and Thioamides as Pesticides | BAYER CROPSCIENCE AG (DE) | 2011-05-19 | — | — | US | disclosed |
| US-20110098287-A1 | Novel Heteroaromatic Amides And Thioamides As Pesticides | BAYER CROPSCIENCE AG (DE) | 2011-04-28 | — | — | US | disclosed |
| EP-2297130-A1 | NOVEL HETEROAROMATIC AMIDES AND THIOAMIDES AS PESTICIDES | Bayer CropScience AG (DE) | 2011-03-23 | — | — | EP | disclosed |
| US-20100317524-A1 | Sulfonylureas | BAYER CROPSCIENCE AG (DE) | 2010-12-16 | — | — | US | disclosed |
| US-20100317524-A1 | Sulfonylureas | BAYER CROPSCIENCE AG (DE) | 2010-12-16 | — | — | US | disclosed |
| WO-2009149858-A1 | NOVEL HETEROAROMATIC AMIDES AND THIOAMIDES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2009-12-17 | — | — | WO | disclosed |
| US-7414011-B2 | Phenylsulfonyl ureas, process for their preparation and their use as herbicides and plant growth regulators | HOECHST SCHERING AGREVO GMBH (US) | 2008-08-19 | — | — | US | disclosed |
| US-7414011-B2 | Phenylsulfonyl ureas, process for their preparation and their use as herbicides and plant growth regulators | HOECHST SCHERING AGREVO GMBH (US) | 2008-08-19 | — | — | US | disclosed |
| EP-1153016-B1 | PHENYLSULFONYL UREAS, METHODS FOR PRODUCING THEM AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2007-09-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160316755-A1 | Novel Heteroaromatic Amides and Thioamides as Pesticides | AADAC, DDT, TST | SMN1; SMN2 4497/4885NPC1 4582/4885ALDH1A1 2960/4885 |
| US-20100317524-A1 | Sulfonylureas | IAPP, SLC5A2, SLC5A1 | SMN1; SMN2 1174/4885NPC1 1114/4885ALDH1A1 1343/4885 |
| US-20170165265-A1 | HEAT SHOCK PROTEIN BINDING COMPOUNDS, COMPOSITIONS, AND METHODS FOR MAKING AND USING SAME | HSPBP1, HSF1, HSPA2 | SMN1; SMN2 270/4885NPC1 2801/4885ALDH1A1 864/4885 |
| US-20110098287-A1 | Novel Heteroaromatic Amides And Thioamides As Pesticides | AADAC, DDT, TST | SMN1; SMN2 4497/4885NPC1 4582/4885ALDH1A1 2960/4885 |
| US-20110118290-A1 | Novel Amides and Thioamides as Pesticides | NAAA, AADAC, PTMS | SMN1; SMN2 3729/4885NPC1 4459/4885ALDH1A1 2966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.