Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 6/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTGIR | P43119 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8273580 | 0.90 | ADAM17 (0.43) | ADAM17MEN1KMT2AKDM4E | |
| SCHEMBL8274900 | 0.87 | ADAM17 (0.53) | ADAM17PTGIRKDM4EPKM | |
| SCHEMBL8221434 | 0.87 | ADAM17 (0.53) | ADAM17PTGIRKDM4EPKM | |
| SCHEMBL8273761 | 0.87 | ADAM17 (0.53) | ADAM17PTGIRKDM4EPKM | |
| SCHEMBL8223154 | 0.84 | CHRM4 (0.46) | ADAM17PTGIRKDM4EPKM | |
| SCHEMBL8273741 | 0.83 | ADAM17 (0.48) | ADAM17KCNQ2MEN1USP2GAA | |
| SCHEMBL8217095 | 0.81 | CHRM4 (0.47) | ADAM17 | |
| SCHEMBL8274406 | 0.77 | ADAM17 (0.49) | ADAM17KCNQ2MEN1USP2GAA | |
| SCHEMBL8273582 | 0.77 | ADAM17 (0.47) | ADAM17MEN1USP2GAAKMT2A | |
| SCHEMBL8275453 | 0.73 | ADAM17 (0.44) | ADAM17MEN1USP2GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121130-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2005-12-22 | — | — | WO | disclosed |