Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 9/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.42 |
| ▸ | PPID | Q08752 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | MTTP | P55157 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8273721 | 0.91 | ADAM17 (0.39) | ADAM17HDAC1HDAC2DPP4HDAC3 | |
| SCHEMBL8273723 | 0.91 | KMT2A (0.42) | ADAM17HDAC1HDAC2DPP4HDAC3 | |
| SCHEMBL8276794 | 0.90 | ADAM17 (0.45) | ADAM17DPP4MTTP | |
| SCHEMBL8273554 | 0.87 | MEN1 (0.45) | ADAM17 | |
| SCHEMBL8273722 | 0.87 | ADAM17 (0.42) | ADAM17DPP4 | |
| SCHEMBL8222060 | 0.85 | ADAM17 (0.54) | ADAM17DPP4MTTP | |
| SCHEMBL8215192 | 0.84 | PTGDR2 (0.43) | ADAM17 | |
| SCHEMBL8273720 | 0.83 | HDAC2 (0.42) | ADAM17HDAC1HDAC2DPP4HDAC3 | |
| SCHEMBL8215091 | 0.82 | MTTP (0.42) | ADAM17MTTP | |
| SCHEMBL8222308 | 0.81 | ADAM17 (0.41) | ADAM17MTTP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121130-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2005-12-22 | — | — | WO | disclosed |