Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 9/20 | 0.44 |
| ▸ | NAMPT | P43490 | 4/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8273559 | 0.90 | MEN1 (0.47) | MEN1NPC1KMT2AADAM17NAMPT | |
| SCHEMBL8215165 | 0.89 | MEN1 (0.45) | MEN1NPC1KMT2AADAM17NAMPT | |
| SCHEMBL8212488 | 0.89 | KMT2A (0.45) | MEN1NPC1KMT2AADAM17NAMPT | |
| SCHEMBL8273275 | 0.88 | ADAM17 (0.48) | ADAM17NAMPTDPP9 | |
| SCHEMBL8273551 | 0.87 | MEN1 (0.46) | MEN1NPC1KMT2AADAM17NAMPT | |
| SCHEMBL8273552 | 0.87 | ADAM17 (0.43) | ADAM17 | |
| SCHEMBL8220550 | 0.87 | MEN1 (0.56) | MEN1NPC1KMT2AADAM17NAMPT | |
| SCHEMBL8212492 | 0.86 | KCNH2 (0.45) | MEN1NPC1KMT2AADAM17NAMPT | |
| SCHEMBL8215172 | 0.86 | ADAM17 (0.51) | MEN1NPC1KMT2AADAM17NAMPT | |
| SCHEMBL8418347 | 0.85 | KMT2A (0.59) | MEN1NPC1KMT2AADAM17NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121130-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2005-12-22 | — | — | WO | disclosed |