Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 19/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8275636 | 0.89 | ADAM17 (0.67) | ADAM17PKM | |
| SCHEMBL8277009 | 0.89 | ADAM17 (0.67) | ADAM17PKM | |
| SCHEMBL8216993 | 0.89 | ADAM17 (0.67) | ADAM17PKM | |
| SCHEMBL8274404 | 0.87 | ADAM17 (0.55) | ADAM17 | |
| SCHEMBL8273746 | 0.81 | ADAM17 (0.59) | ADAM17 | |
| SCHEMBL8273283 | 0.80 | ADAM17 (0.63) | ADAM17 | |
| SCHEMBL8273739 | 0.79 | ADAM17 (0.79) | ADAM17 | |
| SCHEMBL8274406 | 0.78 | ADAM17 (0.49) | ADAM17PKM | |
| SCHEMBL8273741 | 0.76 | ADAM17 (0.48) | ADAM17PKM | |
| SCHEMBL8213114 | 0.76 | ADAM17 (1.00) | ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121130-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2005-12-22 | — | — | WO | disclosed |