Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 19/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8275636 | 1.00 | ADAM17 (0.67) | ADAM17PKM | |
| SCHEMBL8216993 | 1.00 | ADAM17 (0.67) | ADAM17PKM | |
| SCHEMBL8273742 | 0.89 | ADAM17 (0.61) | ADAM17PKM | |
| SCHEMBL8221213 | 0.88 | ADAM17 (0.71) | ADAM17 | |
| SCHEMBL8277006 | 0.88 | ADAM17 (0.71) | ADAM17 | |
| SCHEMBL13542797 | 0.83 | ADAM17 (0.50) | ADAM17 | |
| SCHEMBL8222611 | 0.82 | ADAM17 (0.75) | ADAM17 | |
| SCHEMBL8215141 | 0.81 | ADAM17 (0.74) | ADAM17 | |
| SCHEMBL13541993 | 0.81 | ADAM17 (0.74) | ADAM17 | |
| SCHEMBL8210486 | 0.81 | ADAM17 (0.62) | ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121130-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2005-12-22 | — | — | WO | disclosed |