Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8221026 | 1.00 | ADAM17 (0.51) | ADAM17KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8273353 | 0.87 | ADAM17 (0.61) | ADAM17KDM4EALDH1A1DRD2HTR2A | |
| SCHEMBL8274846 | 0.87 | ADAM17 (0.61) | ADAM17KDM4EALDH1A1DRD2HTR2A | |
| SCHEMBL8274451 | 0.86 | ADAM17 (0.45) | ADAM17ALDH1A1DPP9MEN1KMT2A | |
| SCHEMBL8221408 | 0.86 | ADAM17 (0.51) | ADAM17ALDH1A1DPP4DPP9MEN1 | |
| SCHEMBL8222661 | 0.84 | ADAM17 (0.53) | ADAM17MEN1KMT2ACHRM4 | |
| SCHEMBL8213656 | 0.83 | ADAM17 (0.54) | ADAM17MEN1KMT2ANAMPTCHRM4 | |
| SCHEMBL8222707 | 0.82 | ADAM17 (0.49) | ADAM17MEN1KMT2ANAMPT | |
| SCHEMBL13544350 | 0.82 | ADAM17 (0.47) | ADAM17MEN1KMT2AGAANAMPT | |
| SCHEMBL8213991 | 0.82 | ADAM17 (0.55) | ADAM17ALDH1A1DRD2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121130-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2005-12-22 | — | — | WO | disclosed |