Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 19/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL467427 | 0.81 | SIGMAR1 (0.70) | SIGMAR1HTR2BKCNH2 | |
| SCHEMBL467287 | 0.80 | SIGMAR1 (0.71) | SIGMAR1HTR2BKCNH2 | |
| SCHEMBL467139 | 0.79 | SIGMAR1 (0.72) | SIGMAR1HTR2BKCNH2 | |
| SCHEMBL467162 | 0.77 | SIGMAR1 (0.71) | SIGMAR1 | |
| SCHEMBL466999 | 0.77 | SIGMAR1 (0.73) | SIGMAR1HTR2BKCNH2 | |
| Hydrochloric Acid SCHEMBL1896508 | 0.76 | SIGMAR1 (0.72) | SIGMAR1HTR2BKCNH2 | |
| SCHEMBL1135542 | 0.75 | SIGMAR1 (0.55) | SIGMAR1HTR2BKCNH2 | |
| SCHEMBL8274194 | 0.75 | SIGMAR1 (0.70) | SIGMAR1HTR2BKCNH2 | |
| SCHEMBL23401297 | 0.73 | LMNA (0.53) | LMNA | |
| SCHEMBL8273600 | 0.73 | SIGMAR1 (0.70) | SIGMAR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006021462-A1 | SIGMA RECEPTOR INHIBITORS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2006-03-02 | — | — | WO | disclosed |