Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | CTSS | P25774 | 4/20 | 0.50 |
| ▸ | CTSL | P07711 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 3/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8274278 | 1.00 | LMNA (0.56) | LMNASMN1; SMN2CTSSCTSLHTT | |
| SCHEMBL14617628 | 0.88 | LMNA (0.55) | LMNASMN1; SMN2CTSSCTSLHTT | |
| SCHEMBL2525369 | 0.85 | LMNA (0.55) | LMNASMN1; SMN2CTSSCTSLHTT | |
| SCHEMBL13618128 | 0.85 | LMNA (0.55) | LMNASMN1; SMN2CTSSCTSLHTT | |
| SCHEMBL2525365 | 0.85 | LMNA (0.55) | LMNASMN1; SMN2CTSSCTSLHTT | |
| SCHEMBL2142734 | 0.85 | LMNA (0.58) | LMNASMN1; SMN2CTSSCTSLHTT | |
| SCHEMBL2646824 | 0.85 | LMNA (0.58) | LMNASMN1; SMN2CTSSCTSLHTT | |
| SCHEMBL3701587 | 0.85 | LMNA (0.58) | LMNASMN1; SMN2CTSSCTSLHTT | |
| SCHEMBL8132360 | 0.83 | CTSS (0.53) | LMNASMN1; SMN2CTSSCTSLHTT | |
| SCHEMBL6216286 | 0.82 | LMNA (0.58) | LMNASMN1; SMN2CTSSCTSLHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005111009-A2 | SYNTHESIS OF AMINO ACID KETO-EPOXIDES | PROTEOLIX, INC. (US) | 2005-11-24 | — | — | WO | disclosed |