Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8273347 | 0.87 | ADAM17 (0.56) | ADAM17 | |
| SCHEMBL8276599 | 0.85 | ADAM17 (0.60) | ADAM17 | |
| SCHEMBL8273351 | 0.84 | ADAM17 (0.79) | ADAM17 | |
| SCHEMBL8213654 | 0.84 | ADAM17 (0.79) | ADAM17 | |
| SCHEMBL8219908 | 0.84 | ADAM17 (0.79) | ADAM17 | |
| SCHEMBL8213691 | 0.82 | ADAM17 (0.69) | ADAM17 | |
| SCHEMBL8210486 | 0.82 | ADAM17 (0.62) | ADAM17 | |
| SCHEMBL8276676 | 0.82 | ADAM17 (0.62) | ADAM17 | |
| SCHEMBL8275109 | 0.79 | ADAM17 (0.58) | ADAM17 | |
| SCHEMBL8276165 | 0.77 | ADAM17 (0.54) | ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121130-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2005-12-22 | — | — | WO | disclosed |