Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3315171 | 0.87 | CTSK (0.43) | CTSKKMT2ATSHRHSD17B10ABCB1 | |
| SCHEMBL19595429 | 0.85 | TRPA1 (0.42) | CTSKKMT2ATSHRHSD17B10ABCB1 | |
| SCHEMBL8276846 | 0.84 | HPGD (0.44) | CTSKABCB1CA1CA2KDM4E | |
| SCHEMBL19595090 | 0.84 | HPGD (0.44) | CTSKABCB1CA1CA2KDM4E | |
| SCHEMBL20201946 | 0.83 | TRPA1 (0.43) | CTSKKMT2ATSHRHSD17B10ABCB1 | |
| SCHEMBL8225134 | 0.83 | CTSK (0.40) | CTSKKMT2ATSHRHSD17B10ABCB1 | |
| SCHEMBL2010271 | 0.83 | CTSK (0.40) | CTSKKMT2ATSHRHSD17B10ABCB1 | |
| SCHEMBL2010266 | 0.83 | CTSK (0.40) | CTSKKMT2ATSHRHSD17B10ABCB1 | |
| SCHEMBL29142097 | 0.82 | HPGD (0.45) | CTSKABCB1CA1CA2KDM4E | |
| SCHEMBL16044609 | 0.82 | CTSK (0.41) | CTSKKMT2ATSHRHSD17B10ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121130-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2005-12-22 | — | — | WO | disclosed |