Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5413951 | 0.84 | GLA (0.51) | POLBALDH1A1ALOX15HTTSMN1; SMN2 | |
| SCHEMBL5413945 | 0.84 | GLA (0.51) | POLBALDH1A1ALOX15HTTSMN1; SMN2 | |
| SCHEMBL12721762 | 0.84 | CA2 (0.36) | MEN1KMT2A | |
| SCHEMBL6344332 | 0.80 | MMP1 (0.42) | MMP1MMP2MMP8DPP7MMP3 | |
| SCHEMBL12524298 | 0.80 | MMP1 (0.42) | MMP1MMP2MMP8DPP7MMP3 | |
| SCHEMBL3067845 | 0.75 | DPP7 (0.43) | MMP1MMP2MMP8DPP7DPP4 | |
| SCHEMBL4616011 | 0.74 | MMP1 (0.41) | MMP1MMP2MMP8DPP7DPP4 | |
| SCHEMBL4618200 | 0.74 | MMP1 (0.41) | MMP1MMP2MMP8DPP7DPP4 | |
| SCHEMBL4560650 | 0.72 | MMP1 (0.44) | MMP1MMP2MMP8DPP7DPP4 | |
| SCHEMBL29039191 | 0.71 | CYP1A2 (0.37) | MMP1MMP2MMP8POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121130-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2005-12-22 | — | — | WO | disclosed |