Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.55 |
| ▸ | HTR2C | P28335 | 5/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | HTR7 | P34969 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.45 |
| ▸ | CDK9 | P50750 | 5/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6162919 | 0.88 | HTR2C (0.47) | HTR6HTR2CHTR2AHTR7DRD2 | |
| SCHEMBL5542320 | 0.83 | HTR2C (0.49) | HTR6HTR2CHTR2ADRD2SIGMAR1 | |
| SCHEMBL1513540 | 0.83 | HTR6 (0.50) | HTR6HTR2CHTR2AHTR7DRD2 | |
| Hydrochloric Acid SCHEMBL29882492 | 0.83 | HTR6 (0.50) | HTR6HTR2CHTR2AHTR7DRD2 | |
| SCHEMBL28506378 | 0.81 | HTR2C (0.60) | HTR6HTR2CHTR2AHTR7DRD2 | |
| SCHEMBL3434588 | 0.81 | HTR6 (0.52) | HTR6HTR2CHTR2AHTR7DRD2 | |
| Hydrochloric Acid SCHEMBL2079115 | 0.81 | HTR6 (0.52) | HTR6HTR2CHTR2AHTR7DRD2 | |
| SCHEMBL14320492 | 0.81 | HTR2C (0.46) | HTR6HTR2CHTR7DRD2SIGMAR1 | |
| SCHEMBL5321082 | 0.80 | HTR6 (0.50) | HTR6HTR2CHTR2AHTR7DRD2 | |
| SCHEMBL4702234 | 0.80 | CCNT1 (0.45) | HTR6HTR2CHTR2AHTR7DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005117882-A9 | HYDROXAMIC ACID DERIVATIVES AS METALLOPROTEASE INHIBITORS | INCYTE CORP (US) | 2007-03-01 | — | — | WO | disclosed |