Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3716649 | 0.85 | L3MBTL1 (0.64) | SMN1; SMN2NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL12265783 | 0.83 | SMN1; SMN2 (0.67) | SMN1; SMN2NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL18415475 | 0.80 | SMN1; SMN2 (1.00) | SMN1; SMN2NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL29460273 | 0.80 | SMN1; SMN2 (0.79) | SMN1; SMN2NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL21065524 | 0.80 | SMN1; SMN2 (0.79) | SMN1; SMN2NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL30522589 | 0.80 | SMN1; SMN2 (1.00) | SMN1; SMN2NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL2039123 | 0.80 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL14330463 | 0.80 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL30602600 | 0.79 | SMN1; SMN2 (0.76) | SMN1; SMN2NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL243740 | 0.79 | SMN1; SMN2 (0.76) | SMN1; SMN2NPC1RAB9APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200227644-A1 | ORGANIC LIGHT-EMITTING DIODE OPERABLE AT LOW VOLTAGE WITH HIGH EFFICIENCY AND LONG LIFETIME | SFC CO., LTD. (KR) | 2020-07-16 | — | — | US | disclosed |
| EP-3660934-A1 | ORGANIC LIGHT EMITTING ELEMENT CAPABLE OF DRIVING AT LOW VOLTAGE AND HAVING HIGH EFFICIENCY AND LONG LIFE CHARACTERISTICS | SFC Co., Ltd. (KR) | 2020-06-03 | — | — | EP | disclosed |
| US-8143419-B2 | Trisubstituted 1,2,4-triazoles | JANSSEN PHARMACEUTICA N. V. (BE) | 2012-03-27 | — | — | US | disclosed |
| US-7745021-B2 | Transition metal complex and light-emitting device | FUJIFILM CORPORATION (JP) | 2010-06-29 | — | — | US | disclosed |
| US-20090253691-A1 | TRISUBSTITUTED 1,2,4-TRIAZOLES | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-10-08 | — | — | US | disclosed |
| US-7569852-B2 | Transition metal complex and light-emitting device | FUJIFILM CORPORATION (JP) | 2009-08-04 | — | — | US | disclosed |
| US-20080248329-A1 | TRANSITION METAL COMPLEX AND LIGHT-EMITTING DEVICE | FUJIFILM CORPORATION | 2008-10-09 | — | — | US | disclosed |
| US-20080116453-A1 | TRANSITION METAL COMPLEX AND LIGHT-EMITTING DEVICE | FUJIFILM CORPORATION | 2008-05-22 | — | — | US | disclosed |
| US-20080076738-A1 | Phosphonate Analogs Of Hiv Integrase Inhibitor Compounds | GILEAD SCIENCES, INC. | 2008-03-27 | — | — | US | disclosed |
| US-20080076738-A1 | Phosphonate Analogs Of Hiv Integrase Inhibitor Compounds | GILEAD SCIENCES, INC. | 2008-03-27 | — | — | US | disclosed |
| US-7329898-B2 | Transition metal complex and light-emitting device | FUJIFILM CORPORATION (JP) | 2008-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076738-A1 | Phosphonate Analogs Of Hiv Integrase Inhibitor Compounds | TYMP, PNP, PIKFYVE | SMN1; SMN2 4116/4885NPC1 1365/4885RAB9A 2959/4885 |
| US-20090253691-A1 | TRISUBSTITUTED 1,2,4-TRIAZOLES | CHRNA1, CHRNA5, CHRNA3 | SMN1; SMN2 3305/4885NPC1 2263/4885RAB9A 1835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.