⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28812765 | 0.97 | — | — | |
| SCHEMBL24277958 | 0.80 | TSHR (0.37) | — | |
| SCHEMBL9447285 | 0.75 | — | — | |
| SCHEMBL5720417 | 0.74 | — | — | |
| SCHEMBL24608421 | 0.74 | — | — | |
| SCHEMBL28323840 | 0.74 | NPBWR1 (0.56) | — | |
| SCHEMBL419053 | 0.72 | — | — | |
| SCHEMBL5720433 | 0.72 | — | — | |
| SCHEMBL30443570 | 0.69 | NOTUM (0.47) | — | |
| SCHEMBL14763940 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109627205-A | The preparation method and applications of a kind of carbazyl Isopropanolamine derivatives | 贵州大学 | 2019-04-16 | — | — | CN | claimed |
| CN-108218857-A | A kind of preparation method of pyrrolin and pyridine hydrochloride | 湖南华腾制药有限公司 | 2018-06-29 | — | — | CN | claimed |
| EP-4232153-A1 | MODULATORS OF THE INTEGRATED STRESS RESPONSE PATHWAY | Evotec International GmbH (DE) | 2023-08-30 | — | — | EP | disclosed |
| WO-2023125918-A1 | DNA POLYMERASE THETA INHIBITOR AND USE THEREOF | 上海湃隆生物科技有限公司 | 2023-07-06 | — | — | WO | disclosed |
| WO-2022084446-A1 | MODULATORS OF THE INTEGRATED STRESS RESPONSE PATHWAY | EVOTEC INTERNATIONAL GMBH (DE) | 2022-04-28 | — | — | WO | disclosed |
| CN-109627205-B | Preparation method and application of carbazolyl isopropanolamine derivatives | 贵州大学 | 2022-04-12 | — | — | CN | disclosed |
| US-11005126-B2 | Electrolytic solution for secondary battery, secondary battery, battery pack, electric vehicle, electric power storage system, electric power tool, and electronic device | MURATA MANUFACTURING CO., LTD. (JP) | 2021-05-11 | — | — | US | disclosed |
| US-20190207257-A1 | ELECTROLYTIC SOLUTION FOR SECONDARY BATTERY, SECONDARY BATTERY, BATTERY PACK, ELECTRIC VEHICLE, ELECTRIC POWER STORAGE SYSTEM, ELECTRIC POWER TOOL, AND ELECTRONIC DEVICE | EnviroMix, Inc. | 2019-07-04 | — | — | US | disclosed |
| CN-109627205-A | The preparation method and applications of a kind of carbazyl Isopropanolamine derivatives | 贵州大学 | 2019-04-16 | — | — | CN | disclosed |
| CN-108218857-A | A kind of preparation method of pyrrolin and pyridine hydrochloride | 湖南华腾制药有限公司 | 2018-06-29 | — | — | CN | disclosed |
| EP-2873658-A1 | OXIME-SUBSTITUTED AMIDE COMPOUND AND PEST CONTROL AGENT | Nissan Chemical Industries, Ltd. (JP) | 2015-05-20 | — | — | EP | disclosed |
| US-8143407-B2 | Process for production of heteroaryl-type boron compounds with iridium catalyst | MITSUBISHI RAYON CO., LTD. (JP) | 2012-03-27 | — | — | US | disclosed |
| EP-1481978-B1 | PROCESS FOR PRODUCTION OF HETEROARYL-TYPE BORON COMPOUNDS WITH IRIDIUM CATALYST | MITSUBISHI RAYON CO (JP) | 2011-09-14 | — | — | EP | disclosed |
| US-20100010224-A1 | PROCESS FOR PRODUCTION OF HETEROARYL-TYPE BORON COMPOUNDS WITH IRIDIUM CATALYST | MITSUBISHI RAYON CO., LTD. (JP) | 2010-01-14 | — | — | US | disclosed |
| US-7612218-B2 | Process for production of heteroaryl-type boron compounds with iridium catalyst | MITSUBISHI RAYON CO., LTD. (JP) | 2009-11-03 | — | — | US | disclosed |
| CN-100358883-C | Five-membered aromatic heterocyclic compounds contg. beta-position trifluoromethyl group and synthesis thereof | SHANGHAI INST ORGANIC CHEM (CN) | 2008-01-02 | — | — | CN | disclosed |
| US-20050148775-A1 | Process for production of heteroaryl-type boron compounds with iridium catalyst | MITSUBISHI RAYON CO., LTD. (JP) | 2005-07-07 | — | — | US | disclosed |
| EP-1481978-A1 | PROCESS FOR PRODUCTION OF HETEROARYL-TYPE BORON COMPOUNDS WITH IRIDIUM CATALYST | Mitsubishi Rayon Co., Ltd. (JP) | 2004-12-01 | — | — | EP | disclosed |
| CN-1478077-A | Benzamide compounds as APO B secretion inhibitors | ����ҩƷ��ҵ��ʽ���� | 2004-02-25 | — | — | CN | disclosed |
| CN-1207390-A | Five-membered aromatic heterocyclic compounds contg. beta-position trifluoromethyl group and synthesis thereof | SHANGHAI INST ORGANIC CHEM (CN) | 1999-02-10 | — | — | CN | disclosed |