SCHEMBL9447285

SCHEMBL9447285

FC(F)(F)C(F)(F)C(F)(F)c1ccoc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9447185 0.91 LMNA (0.32)
SCHEMBL827748 0.75
SCHEMBL28812765 0.73
SCHEMBL5720433 0.70
SCHEMBL5720417 0.67
SCHEMBL28943097 0.65 ALDH1A1 (0.46)
SCHEMBL11696796 0.65 TSHR (0.52)
SCHEMBL419053 0.65
SCHEMBL24277958 0.64 TSHR (0.37)
SCHEMBL24473266 0.64 PGK1 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0414906-A1 FLUOROALKYLATED HETEROAROMATIC POLYMER NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1991-03-06 EP claimed
US-5247062-A Hetero-aromatic polymer containing fluoroalkyl group NIPPON OIL AND FATS CP., LTD. (JP) 1993-09-21 US disclosed
EP-0414906-A1 FLUOROALKYLATED HETEROAROMATIC POLYMER NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1991-03-06 EP disclosed