Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.51 |
| ▸ | NCF1 | P14598 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | CHKA | P35790 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | NEK2 | P51955 | 1/20 | 0.44 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL269369 | 0.86 | KDM4E (0.52) | HRH3NCF1CHEK1NEK2LIMK1 | |
| SCHEMBL6530619 | 0.81 | CHKA (0.68) | HRH3NCF1LOXL2CHKAHSD17B10 | |
| SCHEMBL15453232 | 0.80 | HRH3 (0.56) | HRH3NCF1LOXL2CHKAHTR1A | |
| SCHEMBL14359324 | 0.79 | HRH3 (0.60) | HRH3NCF1LOXL2HTR1AADRA1D | |
| SCHEMBL28792044 | 0.78 | HRH3 (0.48) | HRH3NCF1LOXL2CHKAHTR1A | |
| SCHEMBL2937021 | 0.78 | HRH3 (0.45) | HRH3NCF1LOXL2CHKAHTR2C | |
| SCHEMBL10403777 | 0.78 | HRH3 (0.51) | HRH3NCF1LOXL2CHKAHTR1A | |
| SCHEMBL16596266 | 0.77 | HRH3 (0.64) | HRH3NCF1LOXL2CHKAHTR1A | |
| Methane SCHEMBL8954604 | 0.77 | HRH3 (0.47) | HRH3NCF1LOXL2CHKAHTR1A | |
| SCHEMBL30307401 | 0.77 | HRH3 (0.53) | HRH3NCF1LOXL2CHKAADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115710215-B | Phenylethynyl substituted benzenes and heterocycles for the treatment of cancer and uses thereof | 肯塔基大学研究基金会 | 2024-06-04 | — | — | CN | claimed |
| EP-4087889-B1 | STABLE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS 3D PRINTING MATERIALS AND A METHOD OF FABRICATION THEREOF | PROMERUS LLC (US) | 2024-03-06 | — | — | EP | claimed |
| US-11697701-B2 | Stable mass polymerizable polycycloolefin compositions as 3D printing materials and a method of fabrication thereof | PROMERUS, LLC (US) | 2023-07-11 | — | — | US | claimed |
| US-11692056-B2 | Stable polycycloolefin polymer and inorganic nanoparticle compositions as optical materials | PROMERUS, LLC (US) | 2023-07-04 | — | — | US | claimed |
| CN-114938648-B | Stable bulk polymerized polycycloolefin compositions as three-dimensional printing materials and methods of making same | 住友电木株式会社 | 2023-06-30 | — | — | CN | claimed |
| CN-115710215-A | Phenylethynyl substituted benzenes and heterocycles useful in the treatment of cancer and uses thereof | 肯塔基大学研究基金会 | 2023-02-24 | — | — | CN | claimed |
| EP-4087889-A1 | STABLE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS 3D PRINTING MATERIALS AND A METHOD OF FABRICATION THEREOF | Promerus, LLC (US) | 2022-11-16 | — | — | EP | claimed |
| EP-2586893-B1 | COPPER PLATING BATH AND CORRESPONDING METHOD | ROHM & HAAS ELECT MAT (US) | 2022-09-21 | — | — | EP | claimed |
| CN-114938648-A | Stable bulk polymerized polycyclic olefin compositions as three-dimensional printing materials and methods of making same | 普罗米鲁斯有限责任公司 | 2022-08-23 | — | — | CN | claimed |
| US-11299573-B2 | Stable mass polymerizable polycycloolefin compositions as 3D printing materials and a method of fabrication thereof | PROMERUS LLC (US) | 2022-04-12 | — | — | US | claimed |
| CN-114144450-A | Stable polycycloolefin polymers and inorganic nanocomposites as optical materials | 普罗米鲁斯有限责任公司 | 2022-03-04 | — | — | CN | claimed |
| CN-113490527-A | Bicyclic derivatives | 瑞士伊兰科动物保健有限公司 | 2021-10-08 | — | — | CN | claimed |
| US-20210221931-A1 | STABLE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS 3D PRINTING MATERIALS AND A METHOD OF FABRICATION THEREOF | PROMERUS, LLC (US) | 2021-07-22 | — | — | US | claimed |
| WO-2021142402-A1 | STABLE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS 3D PRINTING MATERIALS AND A METHOD OF FABRICATION THEREOF | PROMERUS, LLC (US) | 2021-07-15 | — | — | WO | claimed |
| WO-2021016503-A1 | STABLE POLYCYCLOOLEFIN POLYMER AND INORGANIC NANOPARTICLE COMPOSITIONS AS OPTICAL MATERIALS | PROMERUS, LLC (US) | 2021-01-28 | — | — | WO | claimed |
| US-20210024685-A1 | STABLE POLYCYCLOOLEFIN POLYMER AND INORGANIC NANOPARTICLE COMPOSITIONS AS OPTICAL MATERIALS | PROMERUS, LLC (US) | 2021-01-28 | — | — | US | claimed |
| CN-103103584-A | Plating bath and method | ROHM & HAAS ELECT MAT | 2013-05-15 | — | — | CN | claimed |
| EP-2586893-A2 | Copper plating bath and method | Rohm and Haas Electronic Materials LLC (US) | 2013-05-01 | — | — | EP | claimed |
| US-12037431-B2 | Stable mass polymerizable polycycloolefin compositions as 3D printing materials and a method of fabrication thereof | PROMERUS, LLC (US) | 2024-07-16 | — | — | US | disclosed |
| US-4160837-A | ANTIDEPRESSANTS | CIBA-GEIGY CORPORATION (US) | 1979-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11697701-B2 | Stable mass polymerizable polycycloolefin compositions as 3D printing materials and a method of fabrication thereof | RRP15, PPOX, NONO | HRH3 3703/4885NCF1 2660/4885LOXL2 655/4885 |
| US-12037431-B2 | Stable mass polymerizable polycycloolefin compositions as 3D printing materials and a method of fabrication thereof | RRP15, PPOX, NONO | HRH3 3703/4885NCF1 2660/4885LOXL2 655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.