Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18199929 | 0.74 | PDE4B (0.40) | LMNASMN1; SMN2PTGS2 | |
| SCHEMBL951984 | 0.73 | LMNA (0.55) | KCNH2LMNASMN1; SMN2 | |
| SCHEMBL8154305 | 0.71 | KDM4E (0.39) | SMN1; SMN2 | |
| SCHEMBL10035363 | 0.71 | KCNH2 (0.52) | KCNH2ALOX5 | |
| SCHEMBL22798566 | 0.71 | PRNP (0.44) | LMNASMN1; SMN2HRH2HRH3 | |
| SCHEMBL16106418 | 0.69 | NQO2 (0.41) | LMNA | |
| SCHEMBL20855334 | 0.69 | ALOX5 (0.39) | KCNH2ALOX5PTGS2HRH2HRH3 | |
| SCHEMBL31587740 | 0.69 | LMNA (0.56) | LMNASMN1; SMN2 | |
| SCHEMBL10949246 | 0.68 | MEN1 (0.47) | LMNASMN1; SMN2PTGS2HRH2HRH3 | |
| SCHEMBL2334699 | 0.68 | LMNA (0.59) | LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006007700-A1 | HEPATITIS C INHIBITOR DIPEPTIDE ANALOGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-01-26 | — | — | WO | disclosed |