Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | GFER | P55789 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4875738 | 0.83 | ALDH1A1 (0.52) | ALDH1A1MAPTGFERHTTTDP1 | |
| SCHEMBL8278269 | 0.79 | ALDH1A1 (0.48) | ALDH1A1MAPTGFERHTTTDP1 | |
| SCHEMBL6676320 | 0.77 | ALDH1A1 (0.55) | ALDH1A1MAPTGFERHTTTDP1 | |
| SCHEMBL6676826 | 0.74 | ALDH1A1 (0.51) | ALDH1A1MAPTGFERHTTTDP1 | |
| SCHEMBL6676918 | 0.74 | ALDH1A1 (0.58) | ALDH1A1MAPTGFERHTTTDP1 | |
| SCHEMBL6678303 | 0.74 | ALDH1A1 (0.60) | ALDH1A1MAPTGFERHTTTDP1 | |
| SCHEMBL14018751 | 0.72 | ALDH1A1 (0.63) | ALDH1A1MAPTGFERHTTTDP1 | |
| SCHEMBL8281149 | 0.72 | ALDH1A1 (0.52) | ALDH1A1MAPTGFERHTTTDP1 | |
| SCHEMBL6678265 | 0.72 | MAPT (0.46) | ALDH1A1MAPTGFERHTTTDP1 | |
| SCHEMBL6086664 | 0.71 | CA1 (0.58) | ALDH1A1MAPTGFERHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005090298-A1 | SULPHONAMIDE DERIVATIVES | BIOTIE THERAPIES CORPORATION (FI) | 2005-09-29 | — | — | WO | disclosed |