Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | GFER | P55789 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14018751 | 0.83 | ALDH1A1 (0.63) | ALDH1A1MAPTHTTGFERCA1 | |
| SCHEMBL8281163 | 0.79 | GFER (0.57) | ALDH1A1MAPTHTTGFERCA1 | |
| SCHEMBL8279547 | 0.75 | P2RX1 (0.53) | ALDH1A1MAPTHTTGFERCA1 | |
| SCHEMBL6676320 | 0.74 | ALDH1A1 (0.55) | ALDH1A1MAPTHTTGFERCA1 | |
| SCHEMBL8278269 | 0.74 | ALDH1A1 (0.48) | ALDH1A1MAPTHTTGFERCA1 | |
| SCHEMBL4875738 | 0.72 | ALDH1A1 (0.52) | ALDH1A1MAPTHTTGFERCA1 | |
| SCHEMBL8280271 | 0.72 | ALDH1A1 (0.52) | ALDH1A1MAPTHTTGFERCA1 | |
| SCHEMBL6676078 | 0.72 | ALDH1A1 (0.49) | ALDH1A1MAPTHTTGFERCA1 | |
| SCHEMBL8125111 | 0.72 | GAA (0.54) | ALDH1A1HTTGFERLMNAMAPK1 | |
| SCHEMBL4880800 | 0.71 | MAPT (0.79) | ALDH1A1MAPTHTTGFERCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005090298-A1 | SULPHONAMIDE DERIVATIVES | BIOTIE THERAPIES CORPORATION (FI) | 2005-09-29 | — | — | WO | disclosed |