⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL22660187 | 0.98 | TSHR (0.48) | — | |
| Formic Acid SCHEMBL31187381 | 0.92 | ALDH1A1 (0.47) | — | |
| SCHEMBL27500041 | 0.84 | TSHR (0.64) | — | |
| SCHEMBL9584944 | 0.79 | SIRT2 (0.35) | — | |
| SCHEMBL23928720 | 0.79 | SIRT2 (0.41) | — | |
| SCHEMBL182123 | 0.79 | ALDH1A1 (0.53) | — | |
| SCHEMBL14405077 | 0.78 | — | — | |
| SCHEMBL2933008 | 0.78 | CA12 (0.42) | — | |
| SCHEMBL9212897 | 0.78 | SIRT2 (0.40) | — | |
| SCHEMBL671053 | 0.78 | CA12 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 534 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107652218-A | A kind of pyrrolin ketone derivatives and its application in antineoplastic is prepared | 南方医科大学 | 2018-02-02 | — | — | CN | claimed |
| US-20090014920-A1 | POLYMER FILAMENTS | MASSEY UNIVERSITY (NZ) | 2009-01-15 | — | — | US | claimed |
| WO-2006001719-A1 | POLYMER FILAMENTS | MASSEY UNIVERSITY (NZ) | 2006-01-05 | — | — | WO | claimed |
| EP-4029868-B1 | MCL-1 INHIBITORS | GILEAD SCIENCES INC (US) | 2026-05-20 | — | — | EP | disclosed |
| EP-4739694-A2 | MACROCYCLIC COMPOUNDS AND USE AS TYK2 INHIBITORS | Blossomhill Therapeutics, Inc. (US) | 2026-05-13 | — | — | EP | disclosed |
| EP-4737449-A1 | P53-Y220C SELECTIVE SMALL-MOLECULAR REACTIVATOR COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Changchun Genescience Pharmaceutical Co., Ltd. (CN) | 2026-05-06 | — | — | EP | disclosed |
| EP-4737450-A1 | HETEROAROMATIC FORMAMIDE COMPOUNDS AND USES THEREOF IN MEDICINE | Longwood Pharmaceuticals (Hangzhou) Co., Ltd (CN) | 2026-05-06 | — | — | EP | disclosed |
| WO-2026090477-A1 | HELICASE INHIBITORS AND USES THEREOF | KIMIA THERAPEUTICS, INC. (US) | 2026-04-30 | — | — | WO | disclosed |
| US-20260055116-A1 | SUBSTITUTED TETRAHYDROPYRROLO-PYRIDINONE COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | KARUNA THERAPEUTICS INC (US) | 2026-02-26 | — | — | US | disclosed |
| US-20260022125-A1 | PYRROLOPYRIDAZINE VEGFR INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2026-01-22 | — | — | US | disclosed |
| US-12528792-B2 | Sulfonamide compounds and the use thereof in the treatment of cancer | TroBio Therapeutics Pty Ltd (AU) | 2026-01-20 | — | — | US | disclosed |
| US-4526941-A | Contacting alpha olefin with catalyst comprising organomagnesium compound, titanium compound, nitrogen or sulfur heterocyclic compound, slurry component and organometallic component | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1985-07-02 | — | — | US | disclosed |
| US-4525555-A | TITANIUM COMPOUND SUPPORTED ON SOLID REACTION PRODUCT OF MAGNESIUM HALIDE, SILOXANES, ORGANIC COMPOUNDS | NIPPON OIL COMPANY, LIMITED (JP) | 1985-06-25 | — | — | US | disclosed |
| US-4511575-A | Antidiabetic pyrrolecarboxylic acids | PFIZER INC. (US) | 1985-04-16 | — | — | US | disclosed |
| US-4511576-A | Antidiabetic pyrrolecarboxylic acids | PFIZER INC. (US) | 1985-04-16 | — | — | US | disclosed |
| US-4351843-A | LOWERING BLOOD GLUCOSE | PFIZER INC. (US) | 1982-09-28 | — | — | US | disclosed |
| EP-0052471-A1 | Process and catalyst for polymerization of olefins | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1982-05-26 | — | — | EP | disclosed |
| US-4330650-A | HAVING MAGNESIUM COMPONENTS, TITANIUM COMPONENTS, ORGANOALUMINUM COMPONENTS AND HETEROCYCLIC CARBOXYLIC ESTER ELECTRON DONOR COMPONENTS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1982-05-18 | — | — | US | disclosed |
| US-4282242-A | HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1981-08-04 | — | — | US | disclosed |
| US-4255280-A | ORGANOMAGNESIUM, CHLOROSILANE, TITANIUM, ORGANOMETALLIC AND HETEROCYCLIC ESTER COMPONENTS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1981-03-10 | — | — | US | disclosed |