Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8282352 | 0.95 | CTSV (0.41) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL13693445 | 0.93 | CTSV (0.40) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL14451529 | 0.93 | CTSV (0.40) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL13690180 | 0.93 | CTSV (0.40) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL10141364 | 0.93 | CTSV (0.40) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL16300643 | 0.91 | CTSV (0.39) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL8248558 | 0.90 | CTSV (0.38) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL8248975 | 0.90 | CTSV (0.38) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL14583183 | 0.89 | CTSB (0.38) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL8282348 | 0.88 | CTSV (0.39) | CTSVCTSLCTSBELANECMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005087721-A2 | COMPOUNDS AS INHIBITORS OF HEPATITIS C VIRUS NS3 SERINE PROTEASE | SCHERING CORPORATION (US) | 2005-09-22 | — | — | WO | disclosed |
| WO-2005085242-A1 | NOVEL KETOAMIDES WITH CYCLIC P4'S AS INHIBITORS OF NS3 SERINE PROTEASE OF HEPATITIS C VIRUS | SCHERING CORPORATION (US) | 2005-09-15 | — | — | WO | disclosed |