Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.38 |
| ▸ | LGMN | Q99538 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13817720 | 1.00 | CTSV (0.38) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL14595892 | 1.00 | CTSV (0.38) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL14595896 | 0.90 | CTSV (0.40) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL8280126 | 0.90 | CTSV (0.40) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL8252702 | 0.89 | CTSV (0.39) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL14595897 | 0.89 | CTSV (0.39) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL8243737 | 0.89 | CTSV (0.39) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL14279155 | 0.89 | DPP4 (0.32) | — | |
| SCHEMBL8280125 | 0.88 | CTSV (0.42) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL8257681 | 0.88 | CTSV (0.41) | CTSVCTSLCTSBELANECMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730110-B1 | SULFUR COMPOUNDS AS INHIBITORS OF HEPATITIS C VIRUS NS3 SERINE PROTEASE | SCHERING CORP (US) | 2010-06-09 | — | — | EP | disclosed |
| WO-2005087731-A1 | SULFUR COMPOUNDS AS INHIBITORS OF HEPATITIS C VIRUS NS3 SERINE PROTEASE | SCHERING CORPORATION (US) | 2005-09-22 | — | — | WO | disclosed |