Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | FAP | Q12884 | 2/20 | 0.32 |
| ▸ | PITRM1 | Q5JRX3 | 2/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10274946 | 0.93 | DPP4 (0.32) | DPP4FAPPITRM1DPP8DPP9 | |
| SCHEMBL8253440 | 0.91 | DPP4 (0.34) | DPP4FAPPITRM1DPP8DPP9 | |
| SCHEMBL8244306 | 0.90 | ALDH1A1 (0.30) | — | |
| SCHEMBL8280643 | 0.89 | CTSV (0.32) | — | |
| SCHEMBL13249153 | 0.89 | DPP4 (0.33) | DPP4FAPPITRM1DPP8DPP9 | |
| SCHEMBL14595892 | 0.89 | CTSV (0.38) | — | |
| SCHEMBL8280783 | 0.89 | CTSV (0.38) | — | |
| SCHEMBL13817720 | 0.89 | CTSV (0.38) | — | |
| SCHEMBL10274953 | 0.84 | CTSB (0.33) | DPP4FAPPITRM1DPP8DPP9 | |
| SCHEMBL13818162 | 0.84 | DPP4 (0.40) | DPP4FAPPITRM1DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7342041-B2 | 3,4-(cyclopentyl)-fused proline compounds as inhibitors of hepatitis C virus NS3 serine protease | SCHERING CORPORATION (US) | 2008-03-11 | — | — | US | disclosed |