Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.41 |
| ▸ | ALB | P02768 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | GNPAT | O15228 | 1/20 | 0.39 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24709112 | 1.00 | FOLH1 (0.48) | FOLH1ADRA1ASIRT5ALBALDH1A1 | |
| SCHEMBL24483686 | 0.91 | ADRA1A (0.51) | FOLH1ADRA1ASIRT5ALBEPHX2 | |
| SCHEMBL24558633 | 0.91 | ADRA1A (0.51) | FOLH1ADRA1ASIRT5ALBEPHX2 | |
| SCHEMBL25358474 | 0.89 | FOLH1 (0.52) | FOLH1ALBALDH1A1EPHX2GNPAT | |
| SCHEMBL25358482 | 0.89 | FOLH1 (0.52) | FOLH1ALBALDH1A1EPHX2GNPAT | |
| SCHEMBL19646650 | 0.89 | FOLH1 (0.44) | FOLH1ALBALDH1A1CASP2KDM4E | |
| SCHEMBL21964560 | 0.89 | FOLH1 (0.44) | FOLH1ALBALDH1A1CASP2KDM4E | |
| SCHEMBL16174166 | 0.86 | CASP2 (0.56) | FOLH1ALBCASP2TSHRNAAA | |
| SCHEMBL19862677 | 0.84 | HDAC3 (0.40) | FOLH1SIRT5ALBALDH1A1CASP2 | |
| SCHEMBL16234099 | 0.84 | FOLH1 (0.46) | FOLH1ADRA1ASIRT5ALBEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140335550-A1 | FLUORESCENT SUBSTRATES FOR DETERMINING LYSINE MODIFYING ENZYME ACTIVITY | THE BROAD INSTITUTE, INC. (US) | 2014-11-13 | — | — | US | disclosed |
| US-20140220556-A1 | Method of Design and Synthesis of a New Drug | MARTYNOV ARTUR (UA) | 2014-08-07 | — | — | US | disclosed |
| US-20140220556-A1 | Method of Design and Synthesis of a New Drug | MARTYNOV ARTUR (UA) | 2014-08-07 | — | — | US | disclosed |
| EP-2644617-A1 | METHOD FOR THE MOLECULAR DESIGN AND SYNTHESIS OF THERAPEUTIC AND PREVENTIVE DRUGS | Farber, Boris Slavinovich (RU) | 2013-10-02 | — | — | EP | disclosed |
| US-20120130699-A1 | Method of molecular design and synthesis of therapeutic and preventive drugs | MARTYNOV ARTUR (UA) | 2012-05-24 | — | — | US | disclosed |
| US-20120130699-A1 | Method of molecular design and synthesis of therapeutic and preventive drugs | MARTYNOV ARTUR (UA) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140335550-A1 | FLUORESCENT SUBSTRATES FOR DETERMINING LYSINE MODIFYING ENZYME ACTIVITY | MAN2B1, KDM1A, KDM3A | FOLH1 525/4885ADRA1A 2968/4885SIRT5 1132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.