Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MMP2 | P08253 | 5/20 | 0.41 |
| ▸ | MMP9 | P14780 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4615466 | 0.84 | CTSK (0.77) | CTSK | |
| SCHEMBL4615469 | 0.84 | CTSK (0.77) | CTSK | |
| SCHEMBL4615462 | 0.84 | CTSK (0.77) | CTSK | |
| SCHEMBL56831 | 0.83 | MMP1 (0.51) | CTSKMMP2MMP9ADAM17 | |
| SCHEMBL61244 | 0.83 | CTSK (0.48) | CTSKPOLBMMP2MMP9ADAM17 | |
| SCHEMBL22289434 | 0.74 | PLCG1 (0.55) | CTDSP1POLBMAPK1HTTALDH1A1 | |
| SCHEMBL8281066 | 0.74 | MAPK1 (0.56) | MMP2MMP9MAPK1HTTALDH1A1 | |
| SCHEMBL4613170 | 0.73 | CTSK (0.78) | CTSK | |
| SCHEMBL4614324 | 0.73 | CTSK (0.78) | CTSK | |
| SCHEMBL4613061 | 0.73 | CTSK (0.78) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092844-A1 | NONPEPTIDE INHIBITORS OF MATRIX METALLOPROTEINASES | SOUTHERN RESEARCH INSTITUTE (US) | 2005-10-06 | — | — | WO | disclosed |