SCHEMBL828158

SCHEMBL828158

C=C[SiH](C=C)CCCCCl

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27981665 0.92
SCHEMBL1271786 0.79
SCHEMBL5341512 0.65
SCHEMBL523017 0.63
SCHEMBL21800 0.62
Vinyl Chloride SCHEMBL26926451 0.61
SCHEMBL4536124 0.61 TSHR (0.40) ALDH1A1TSHRTDP1
SCHEMBL6841037 0.61
SCHEMBL5881449 0.61
SCHEMBL4528581 0.61 TSHR (0.40) ALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022239631-A1 NOVEL TERMINAL-MODIFIED POLYPHENYLENE ETHER AND TERMINAL-MODIFIED POLYPHENYLENE ETHER COMPOSITION 旭化成株式会社 2022-11-17 WO disclosed
WO-2020116367-A1 POLYBUTADIENE AND METHOD FOR PRODUCING SAME 宇部興産株式会社 2020-06-11 WO disclosed
EP-2199296-B1 Organic silicon compounds SHINETSU CHEMICAL CO (JP) 2012-06-27 EP disclosed
US-8197903-B2 Surface modified organic inorganic hybrid glass, protecting group induced alcohol or its derivative and producing method thereof INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIVERSITY (KR) 2012-06-12 US disclosed
US-8143359-B2 Organic silicone compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-27 US disclosed
EP-1452549-B1 PROCESS FOR PRODUCING MODIFIED POLYMER, APPARATUS FOR PRODUCING MODIFIED POLYMER, AND MODIFIED POLYMER SEKISUI CHEMICAL CO LTD (JP) 2010-11-17 EP disclosed
US-20100160588-A1 ORGANIC SILICONE COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-06-24 US disclosed
EP-2199296-A1 Organic silicone compound Shin-Etsu Chemical Co., Ltd. (JP) 2010-06-23 EP disclosed
US-7629419-B2 Process for producing modified polymer, apparatus for producing modified polymer, and modified polymer SEKISUI CHEMICAL CO., LTD. (JP) 2009-12-08 US disclosed
US-20090274910-A1 Surface Modified Organic Inorganic Hybrid Glass, Protecting Group Induced Alcohol or Its Derivative and Producing Method Thereof INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2009-11-05 US disclosed
WO-2007120014-A1 SURFACE MODIFIED ORGANIC·INORGANIC HYBRID GLASS, PROTECTING GROUP INDUCED ALCOHOL OR ITS DERIVATIVE AND PRODUCING METHOD THEREOF INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2007-10-25 WO disclosed
US-20050053792-A1 High purity; using supercritical fluid; high temperature; high pressure; polyolefins; interface film for glass; ceramic binder SEKISUI CHEMICAL CO., LTD. (JP) 2005-03-10 US disclosed
EP-1452549-A1 PROCESS FOR PRODUCING MODIFIED POLYMER, APPARATUS FOR PRODUCING MODIFIED POLYMER, AND MODIFIED POLYMER SEKISUI CHEMICAL CO., LTD. (JP) 2004-09-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090274910-A1 Surface Modified Organic Inorganic Hybrid Glass, Protecting Group Induced Alcohol or Its Derivative and Producing Method Thereof VIM, ICAM1, ILK ALDH1A1 201/4885TSHR 3919/4885TDP1 4523/4885
US-20100160588-A1 ORGANIC SILICONE COMPOUND OR10J3, FOXO1, OR51E2 ALDH1A1 2040/4885TSHR 2305/4885TDP1 3773/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.