Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 19/20 | 0.52 |
| ▸ | AVPR1A | P37288 | 15/20 | 0.52 |
| ▸ | AVPR2 | P30518 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8281643 | 1.00 | OXTR (0.52) | OXTRAVPR1AAVPR2MEN1KMT2A | |
| SCHEMBL8282551 | 0.90 | OXTR (0.54) | OXTRAVPR1AAVPR2MEN1KMT2A | |
| SCHEMBL8279850 | 0.88 | OXTR (0.55) | OXTRAVPR1AAVPR2 | |
| SCHEMBL8282612 | 0.88 | OXTR (0.55) | OXTRAVPR1AAVPR2 | |
| SCHEMBL8279860 | 0.88 | OXTR (0.50) | OXTRAVPR1AAVPR2MEN1KMT2A | |
| SCHEMBL8281024 | 0.87 | OXTR (0.62) | OXTRAVPR1AAVPR2 | |
| SCHEMBL8281748 | 0.87 | OXTR (0.62) | OXTRAVPR1AAVPR2 | |
| SCHEMBL8281026 | 0.87 | OXTR (0.63) | OXTRAVPR1AAVPR2 | |
| SCHEMBL8279852 | 0.87 | OXTR (0.63) | OXTRAVPR1AAVPR2 | |
| SCHEMBL8281687 | 0.86 | OXTR (0.48) | OXTRAVPR1AAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082866-A2 | SUBSTITUTED 1, 2, 4- TRIAZOLE DERIVATIVES AS OXYTOCIN ANTAGONISTS | PFIZER LIMITED (GB) | 2005-09-09 | — | — | WO | disclosed |