Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 10/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | RAF1 | P04049 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6259886 | 1.00 | VCAM1 (0.57) | VCAM1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL13495791 | 0.85 | MAPT (0.68) | MAPTALDH1A1HPGDGAANPC1 | |
| SCHEMBL6260994 | 0.82 | ALDH1A1 (0.57) | VCAM1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4586022 | 0.80 | VCAM1 (0.63) | VCAM1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8280952 | 0.80 | VCAM1 (0.63) | VCAM1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL30811551 | 0.78 | VCAM1 (0.74) | VCAM1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL239454 | 0.78 | VCAM1 (0.74) | VCAM1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6473 | 0.78 | VCAM1 (0.74) | VCAM1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL5313736 | 0.77 | NPC1 (0.63) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL5313730 | 0.77 | NPC1 (0.63) | MAPTALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005072741-A1 | ((11-OXO-10,11-DIHYDRODIBENZO [B, F] [1, 4] OXAZEPIN-1-YL)OXY) ACETIC ACID DERIVATIVES AND RELATED COMPOUNDS AS CARDIOVASCULAR PREPARATIONS USED TO TREAT ARTERIOLOSCLEROSIS | BAYER HEALTHCARE AG (DE) | 2005-08-11 | — | — | WO | disclosed |