Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8282999 | 0.76 | KMT2A (0.42) | POLBGAASMN1; SMN2 | |
| SCHEMBL8407582 | 0.75 | — | — | |
| SCHEMBL12600794 | 0.74 | F2 (0.46) | POLBGAASMN1; SMN2 | |
| SCHEMBL5002371 | 0.69 | SMN1; SMN2 (0.56) | POLBGAASMN1; SMN2 | |
| SCHEMBL4553513 | 0.69 | CYP3A4 (0.41) | POLBGAASMN1; SMN2 | |
| SCHEMBL2556169 | 0.67 | POLB (0.38) | POLBGAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5106808 | 0.66 | SMN1; SMN2 (0.38) | POLBGAASMN1; SMN2 | |
| SCHEMBL11363846 | 0.66 | ALDH1A1 (0.44) | POLBGAASMN1; SMN2 | |
| SCHEMBL11398119 | 0.66 | POLB (0.41) | POLBGAASMN1; SMN2 | |
| SCHEMBL8282178 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005085242-A1 | NOVEL KETOAMIDES WITH CYCLIC P4'S AS INHIBITORS OF NS3 SERINE PROTEASE OF HEPATITIS C VIRUS | SCHERING CORPORATION (US) | 2005-09-15 | — | — | WO | disclosed |