Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | BRD2 | P25440 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8407582 | 0.88 | — | — | |
| SCHEMBL8282173 | 0.76 | POLB (0.42) | POLBGAASMN1; SMN2 | |
| SCHEMBL719466 | 0.72 | F2 (0.48) | KMT2AMEN1POLBCHRM2CHRM4 | |
| SCHEMBL9344572 | 0.72 | KMT2A (0.42) | KMT2AMEN1POLBCHRM2CHRM4 | |
| SCHEMBL7279979 | 0.72 | KMT2A (0.42) | KMT2AMEN1POLBCHRM2CHRM4 | |
| SCHEMBL10799321 | 0.72 | KMT2A (0.42) | KMT2AMEN1POLBCHRM2CHRM4 | |
| SCHEMBL6044381 | 0.72 | KMT2A (0.42) | KMT2AMEN1POLBCHRM2CHRM4 | |
| SCHEMBL3880356 | 0.72 | CHRM2 (0.45) | KMT2AMEN1POLBCHRM2CHRM4 | |
| SCHEMBL8283745 | 0.69 | HTR1A (0.43) | CYP1A2CYP2C9HTR1AADRA1BSMN1; SMN2 | |
| SCHEMBL11325829 | 0.69 | MEN1 (0.40) | KMT2AMEN1POLBCHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005085242-A1 | NOVEL KETOAMIDES WITH CYCLIC P4'S AS INHIBITORS OF NS3 SERINE PROTEASE OF HEPATITIS C VIRUS | SCHERING CORPORATION (US) | 2005-09-15 | — | — | WO | disclosed |