Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16437062 | 0.77 | L3MBTL1 (0.55) | ALDH1A1L3MBTL1GLAALOX15MAPT | |
| 1,2-Diethoxybenzene SCHEMBL29428929 | 0.77 | ALDH1A1 (0.68) | ALDH1A1L3MBTL1GLAALOX15MAPT | |
| 1,2-Diethoxybenzene SCHEMBL578986 | 0.77 | ALDH1A1 (0.68) | ALDH1A1L3MBTL1GLAALOX15MAPT | |
| SCHEMBL12514658 | 0.76 | HTT (0.54) | ALDH1A1MAPTGAAHSD17B10TDP1 | |
| SCHEMBL12662425 | 0.76 | CA1 (0.55) | ALDH1A1L3MBTL1ALOX15MAPTHPGD | |
| 1,2-Diethoxybenzene SCHEMBL28608089 | 0.73 | L3MBTL1 (0.61) | ALDH1A1L3MBTL1GLAALOX15MAPT | |
| 1-Hydroxy-2-Ethoxybenzene SCHEMBL28519 | 0.71 | GAA (0.64) | ALDH1A1L3MBTL1GLAMAPTNPSR1 | |
| 1-Hydroxy-2-Ethoxybenzene SCHEMBL29579232 | 0.71 | GAA (0.64) | ALDH1A1L3MBTL1GLAMAPTNPSR1 | |
| SCHEMBL10638286 | 0.71 | L3MBTL1 (0.59) | ALDH1A1L3MBTL1GLAALOX15MAPT | |
| 1-Hydroxy-2-Ethoxybenzene SCHEMBL28239475 | 0.71 | GAA (0.64) | ALDH1A1L3MBTL1GLAMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005070916-A1 | THIOPHENE AND FURAN COMPOUNDS | ELI LILLY AND COMPANY (US) | 2005-08-04 | — | — | WO | disclosed |