Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 5/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21495034 | 0.81 | PDE5A (0.51) | ALDH1A1ABL1MEN1KMT2AMAPT | |
| SCHEMBL8350301 | 0.81 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL6036808 | 0.81 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL7493963 | 0.81 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL7488591 | 0.78 | KMT2A (0.53) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL8283113 | 0.78 | SMN1; SMN2 (0.57) | ALDH1A1ABL1MEN1KMT2APOLB | |
| SCHEMBL11359245 | 0.77 | GABRA5 (0.57) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL2788439 | 0.77 | SMN1; SMN2 (0.69) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL28100058 | 0.77 | GABRA5 (0.71) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL7845357 | 0.77 | GABRA5 (0.71) | ALDH1A1MEN1KMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005072731-A1 | 3-PHENYL-N- ((1, 3, 4) THIADIAZOL-2-YL) -ACRYLAMIDE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS OF ESTROGEN-RELATED RECEPTORS FOR THE TREATMENT OF E.G. CANCER, RHEUMATOID ARTHRITIS OR NEUROLOGICAL DISORDERS | X-CEPTOR THERAPEUTICS, INC. (US) | 2005-08-11 | — | — | WO | disclosed |