Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | REN | P00797 | 8/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | CTSE | P14091 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7860628 | 1.00 | CTSK (0.47) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL9516912 | 0.96 | CTSS (0.52) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL8621724 | 0.96 | CTSS (0.52) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL9515615 | 0.96 | CTSS (0.52) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL13134798 | 0.96 | CTSS (0.52) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL10775664 | 0.96 | CTSS (0.52) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL13430899 | 0.94 | CTSK (0.49) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL14921350 | 0.90 | CTSS (0.46) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL8284381 | 0.88 | CA1 (0.41) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL13347448 | 0.88 | CTSK (0.48) | CTSKCTSSCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005085275-A1 | INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE | SCHERING CORPORATION (US) | 2005-09-15 | — | — | WO | disclosed |