Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5524487 | 1.00 | CTSK (0.44) | CTSKKMT2AALDH1A1L3MBTL1TSHR | |
| SCHEMBL5524483 | 1.00 | CTSK (0.44) | CTSKKMT2AALDH1A1L3MBTL1TSHR | |
| SCHEMBL14507999 | 1.00 | CTSK (0.44) | CTSKKMT2AALDH1A1L3MBTL1TSHR | |
| SCHEMBL3622543 | 0.89 | CTSK (0.44) | CTSKKMT2AALDH1A1L3MBTL1TSHR | |
| SCHEMBL5529617 | 0.89 | CTSK (0.44) | CTSKKMT2AALDH1A1L3MBTL1TSHR | |
| SCHEMBL5462513 | 0.89 | CTSK (0.44) | CTSKKMT2AALDH1A1L3MBTL1TSHR | |
| SCHEMBL5418010 | 0.84 | ALDH1A1 (0.50) | KMT2AALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL3619257 | 0.82 | CTSK (0.47) | CTSKKMT2AALDH1A1TSHRHSD17B10 | |
| SCHEMBL5469248 | 0.82 | CTSK (0.47) | CTSKKMT2AALDH1A1TSHRHSD17B10 | |
| SCHEMBL13937535 | 0.81 | CTSK (0.41) | CTSKKMT2AALDH1A1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005074904-A2 | SILINANE COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-08-18 | — | — | WO | disclosed |