Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.41 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5326209 | 0.86 | ALDH1A1 (0.50) | ALDH1A1KDM4EUSP2IMPDH2IMPDH1 | |
| SCHEMBL8777864 | 0.85 | ALDH1A1 (0.58) | ALDH1A1KDM4EUSP2IMPDH2IMPDH1 | |
| SCHEMBL5652331 | 0.85 | SRC (0.46) | ALDH1A1KDM4EUSP2AREGFR | |
| SCHEMBL20866202 | 0.85 | SRC (0.46) | ALDH1A1KDM4EUSP2AREGFR | |
| SCHEMBL16664689 | 0.84 | ALDH1A1 (0.49) | ALDH1A1KDM4EUSP2IMPDH2IMPDH1 | |
| SCHEMBL31716249 | 0.84 | ALDH1A1 (0.49) | ALDH1A1KDM4EUSP2IMPDH2IMPDH1 | |
| SCHEMBL21996461 | 0.84 | ALDH1A1 (0.49) | ALDH1A1KDM4EUSP2NPC1IMPDH2 | |
| SCHEMBL28902119 | 0.84 | POLB (0.52) | ALDH1A1KDM4EUSP2IMPDH2IMPDH1 | |
| SCHEMBL13720176 | 0.84 | KDM4E (0.49) | ALDH1A1KDM4EUSP2NPC1IMPDH2 | |
| SCHEMBL11153594 | 0.84 | NPC1 (0.60) | ALDH1A1KDM4EUSP2NPC1IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 327 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119176746-B | Method for preparing bisphenol A and heterocyclic compound by using waste PC | 浙江大学 | 2025-05-30 | — | — | CN | claimed |
| CN-119176746-A | Method for preparing bisphenol A and heterocyclic compound by using waste PC | 浙江大学 | 2024-12-24 | — | — | CN | claimed |
| CN-118440013-A | Preparation method of quinazoline diketone compound | 安顺学院 | 2024-08-06 | — | — | CN | claimed |
| CN-114380718-B | Acylation method of aniline compound | 河南农业大学 | 2022-09-30 | — | — | CN | claimed |
| CN-114380718-A | Acylation method of aniline compound | 河南农业大学 | 2022-04-22 | — | — | CN | claimed |
| CN-106946800-B | A kind of synthetic method of -2,4 (1H, 3H)-diketone of quinazoline and its derivative | 华东师范大学 | 2019-11-15 | — | — | CN | claimed |
| CN-106946800-A | A kind of synthetic method of (1H, the 3H) diketone of quinazoline 2,4 and its derivative | 华东师范大学 | 2017-07-14 | — | — | CN | claimed |
| CN-104059075-B | 8,9-is mono-, disubstituted imidazoles [1,2-c]-quinazoline-3 (2H)-one fused heterocyclic compound and preparation method thereof | ZAOZHUANG UNIVERSITY (CN) | 2015-10-21 | — | — | CN | claimed |
| CN-101747323-B | Method for preparing alfuzosin hydrochloride | BEIJING INST TECHNOLOGY | 2013-04-17 | — | — | CN | claimed |
| CN-101747323-A | Method for preparing alfuzosin hydrochloride | BEIJING INST TECHNOLOGY | 2010-06-23 | — | — | CN | claimed |
| US-6336963-B1 | INK COMPOSITION COMPRISING INK VEHICLE COMPRISING FIRST NITRILE COMPOUND HAVING FIRST VISCOSITY AT MELT TEMPERATURE, VISCOSITY MODIFIER COMPRISING SECOND NITRILE COMPOUND HAVING LOWER VISCOSITY AT MELT TEMPERATURE, COLORANT | XEROX CORPORATION | 2002-01-08 | — | — | US | claimed |
| EP-0308059-B1 | 1,2,3,4-TETRAHYDROISOQUINOLINE ANTIARRHYTHMIC AGENTS | Pfizer Limited (GB) | 1992-09-09 | — | — | EP | claimed |
| EP-0308059-A1 | 1,2,3,4-Tetrahydroisoquinoline antiarrhythmic agents | Pfizer Limited (GB) | 1989-03-22 | — | — | EP | claimed |
| WO-2025227032-A1 | METHODS FOR DEGRADATION OF CYCLIN K AND INHIBITION OF CYCLIN DEPENDENT KINASES | REMIX THERAPEUTICS INC. (US) | 2025-10-30 | — | — | WO | disclosed |
| CN-120665049-A | Convenient synthetic method of bunazosin | 昭通学院 | 2025-09-19 | — | — | CN | disclosed |
| CN-119176746-B | Method for preparing bisphenol A and heterocyclic compound by using waste PC | 浙江大学 | 2025-05-30 | — | — | CN | disclosed |
| US-4060615-A | ANTIHYPERTENSIVE, PHOSPHODIESTERASE INHIBITOR | MEAD JOHNSON & COMPANY (US) | 1977-11-29 | — | — | US | disclosed |
| US-4001269-A | 3-AMINO-5,6-DIMETHOXYINDAZOLE HYDROCHLORIDE | MORTON-NORWICH PRODUCTS, INC. (US) | 1977-01-04 | — | — | US | disclosed |
| US-3980650-A | 4-Amino-pyrimidine derivatives | N.V. KONINKLIJKE PHARMACEUTISCHE FABRIEKEN V/H BROCADES-STHEEMAN EN PHARMACIA (NL) | 1976-09-14 | — | — | US | disclosed |
| US-3935213-A | Process for hypotensive 4-amino-2-(piperazin-1-yl) quinazoline derivatives | PFIZER INC. (US) | 1976-01-27 | — | — | US | disclosed |